From a Spanish title of the Virgin Mary, Nuestra Señora de Guadalupe, meaning "Our Lady of Guadalupe". Guadalupe is a Spanish place name, the site of a famous convent, derived from Arabic وادي (wadi) meaning "valley, river" possibly combined with Latin lupus meaning "wolf". In the 16th century Our Lady of Guadalupe supposedly appeared in a vision to a native Mexican man, and she is now regarded as a patron saint of the Americas.